LATAM Specialty Partner Proposal

Ophthalmic Aesthetics Commercialization Deck

An optimized, shared-risk distribution model for launching premium cash-pay lifestyle eye drops across high-growth Latin American medical clinics.

De-Risked Licensing and Partnership Proposal for US Innovators

Why Partner With Us?

As an established regional specialty partner, we offer US pharmaceutical innovators a fully localized, turn-key commercialization ecosystem. We bypass public healthcare system delays and price controls by targeting the booming private, cash-pay aesthetics sector, mobilizing premium medical networks, and managing localized cold-chain logistics directly to point-of-sale.

Direct Detailing

Private Clinic Detail Network

We detail directly to the region's elite private ophthalmology, oculoplastic, and premium dermatology clinics, driving high-value peer-to-peer adoption.

Channel Placement

Premium Retail Penetration

We secure preferred product placement across high-income private pharmacy networks and specialized aesthetic distribution outlets.

Regulatory Sponsoring

Sovereign Regulatory Sponsorship

We act as your local Marketing Authorization Holder, navigating ANVISA, COFEPRIS, and regional agencies on optimized private pathways.

Latin America Is a Strong Growth Opportunity at the Intersection of Aesthetics and Ophthalmology

Latin America combines strong aesthetic demand, expanding private healthcare capacity, and growing interest in minimally invasive treatments. Unlike many therapeutic categories, aesthetic procedures are primarily cash-pay, making adoption less dependent on reimbursement and more dependent on physician awareness, patient demand, and perceived value.

34.9M
Global Aesthetic Procedures In 2023

ISAPS reported 34.9 million aesthetic procedures performed by plastic surgeons worldwide in 2023, underscoring the scale of patient demand behind periocular and facial-aesthetics adoption.

Annual Aesthetic Procedures By Launch Market (ISAPS 2023)

Source-backed procedure counts show why Mexico and Colombia work as a concentrated proof-of-concept, while Brazil is the logical next expansion market. Venezuela remains a selective watchlist opportunity, but is not included in this chart until comparable published procedure data is available.

Commercial Relevance

Mexico and Colombia Provide a Concentrated Launch Base

Mexico and Colombia offer an attractive first-stage launch base because they combine meaningful aesthetic procedure volume with relevant ophthalmology infrastructure. That combination is especially important for a product positioned at the intersection of periocular aesthetics and ophthalmic care.

Mexico

Launch Market

ISAPS estimates approximately 1.7 million aesthetic procedures annually in Mexico, including more than 782,000 non-surgical procedures, nearly 588,000 injectable procedures, and more than 83,000 eyelid surgeries.

Plastic Surgeons
2,394
Ophthalmologists
5,459

Colombia

Focused Launch Market

ISAPS estimates approximately 447,000 aesthetic procedures annually in Colombia, including more than 176,000 non-surgical procedures, nearly 126,000 injectable procedures, and approximately 25,000 eyelid surgeries.

Plastic Surgeons
825
Ophthalmologists
1,997

Combined Opportunity Snapshot

Together, Mexico and Colombia represent approximately 2.16 million annual aesthetic procedures, more than 958,000 non-surgical aesthetic procedures, more than 713,000 injectable procedures, and more than 108,000 eyelid surgeries. This creates a commercially relevant foundation for a staged launch strategy focused on physician education, periocular aesthetics, and category creation.

Brazil as the Logical Next Market

Beyond the initial Mexico and Colombia focus, Brazil materially expands the regional opportunity. With more than 3 million annual aesthetic procedures, it is a logical next market once early commercial and operational milestones are achieved.

Selective Expansion Watchlist

Venezuela as a Selective High-Upside Watchlist

Venezuela appears commercially relevant again in specific private-pay pockets, especially where premium pharmacy retail, dollar-linked spending, and urban specialist care are re-emerging. But we should frame it as a selective expansion market rather than a first-wave launch because sanctions, FX volatility, import friction, and infrastructure reliability can still materially affect execution.

Conservative Base Case, With Directional Expanded Upside

Directional Upside Only

The current base estimate remains conservative because it uses published acquired ptosis prevalence data. The broader aesthetic opportunity can be significantly larger, but that upside should be framed directionally rather than as published epidemiology.

Cosmetic or perceived "tired eyes" Mild periocular aging concerns Post-Botox lid drop Broader aesthetic enhancement demand

Estimated extended opportunity includes consumers seeking improvement in tired-eye appearance, periocular aging, post-Botox lid drop, and other aesthetic eyelid concerns. These figures should be presented as directional estimates generated from market analogs and AI-assisted modeling, not as published epidemiological studies.

Optimizing the Partnership Framework

Aesthetics out-licensing requires substantial distributor marketing investment to build brand awareness. To establish a sustainable business case, we propose a de-risked structure that shifts focus from high fixed costs to flexible, performance-driven incentives.

Proposed Value-Chain Allocation

Model Comparison Select

1

Licensor Transfer Price (35%)

A standard fixed transfer price of 35% NSP ensures immediate margins for the US partner, but limits regional volume-scaling capabilities.

2

Commitment To Marketing (25%)

We commit 25% of net sales to doctor masterclasses, local symposia, and visual consumer digital outreach.

3

Channel Management (40%)

Covers local specialized sales force deployment, cold-chain distribution logistics, and private pharmacy stocking margins.

Partner Fit

Why We Are the Right LATAM Partner

We combine medical, operational, and commercial expertise under one structure. That matters because success in LATAM depends not only on distribution, but also on physician education, periocular-aesthetics credibility, regulatory execution, and disciplined market creation in private-pay settings.

Clinical and Category Expertise

Led by a U.S.-licensed, board-certified ophthalmologist with direct exposure to both U.S. clinical standards and Latin American healthcare realities.

This gives the program physician-facing credibility across ophthalmology, oculoplastics, and periocular aesthetics while supporting the education required to build a new prescription-led category.

Regulatory and Operational Execution

Leadership experience across medical affairs, clinical development, pharmacovigilance, regulatory affairs, and specialty pharmaceutical commercialization supports country-by-country launch planning.

That includes importation pathways, health-authority coordination, compliance requirements, distributor models, and launch-readiness execution.

Brand Development and Market Creation

We bring healthcare-focused brand strategy, physician education planning, audience intelligence, and consumer-facing communication needed to position Upneeq at the intersection of ophthalmology and aesthetics.

This is especially relevant in LATAM, where market adoption in private-pay categories depends on both doctor conviction and patient-perceived value.

Our Capabilities vs. Standard Distributors

Business Case and Resource Architect

3-Year Financial, FTE and Geo-Targeting Modeler

Simulate our commercialization plan. Adjust our target field deployment, clinic coverage goals, and product pricing to see our projected financial commitment to your brand.

Plan Core Variables

Acquired Ptosis / Eye-Lift Drops

Field Force and Detailing Benchmarks

Aesthetic Rep Annual Base Salary (USD) $35,000
Target Annual Product Details per Rep 1,200
Projected 3-Yr Sales Potential
$0.0M
Based on private clinic tiers
Our Planned Field Deployment
0 FTEs
Reps, MSLs, KAMs, Digital
Our Local Launch Investment
$0.0M
SGA and Field Force Co-Op

Our Proposed 3-Year Revenue and Promotional Allocation Model

Our Localized Geographic Targets and Patient Segmentation Plan

Affluent Micro-Target Hotspots

Loading target micro-geographies...

Target Patient Segments

High-net-worth ocular aesthetic seekers, premium presbyopic professionals, beauty-conscious patients, and luxury ocular wellness buyers.

Our Commercialization Channels

Direct doctor clinic dispensing, exclusive launch gala symposiums, and localized private-pay e-commerce patient support systems.

Partner Launch Readiness View

Ptosis Launch Timeline and Regulatory Snapshot

A simplified partner-facing view focused on acquired ptosis only. Use it to discuss expected time to launch, reliance posture, budget range, and practical packaging considerations by market.

Partner Inputs

This version stays locked to acquired ptosis / eye-lift drops.

Product Focus
Acquired Ptosis / Eye-Lift Drops
Climate / Packaging Watchout
Warm-zone logistics planning required
CZ

Important to Keep in Mind
    Regulatory Window
    Estimated Time to Launch
    Reliance Position
    Indicative Local Budget

    Illustrative Critical Path

    A partner-friendly view of the likely filing-to-launch sequence.

    Reliance and Evidence Notes

    These points help frame what the local team usually needs from the originator dossier.